The SHFJ is a research center dedicated to molecular and functional non-invasive imaging for clinical and preclinical research in oncology, neurology, neurodegenerative disease and psychiatry. The facility includes a nuclear medicine unit and is located in Orsay's Hospital area (near Paris).
<div class="ExternalClass0CEECC93DD5C417A9817D8E54EA099C7"><p>Molecular Imaging Research Center is a preclinical research installation created by the CEA and INSERM. This installation, consists of a group of platforms dedicated to the development of animal models pertinent to human diseases.</p></div>
NeuroSpin is a research center built to develop and validate neuroimaging using ultra-high Magnetic Field headed by Dr. Denis Le Bihan, a Member of the French Academy of Sciences. It was opened on January 1st 2007. The center is recognized as a large infrastructure, for biomedical imaging, such as the CERN in Genève. It is a shared imaging facility with unique imaging devices,. An 11.7T MRI scanner for human will be installed in 2016, one of the first in the world.
The Institute of Biomedicale Imaging take part in three projects: CATI, INUMAC project and Human Brain Project.
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The facilities of CRC MIRCen are dedicated to the exploration and validation of concepts and the preclinical evaluation of new treatment strategies in the domains of gene, cell and drug-based therapies, principally for neurodegenerative diseases.
This platform offers methods, equipment and expertise in biochemistry, cell culture and molecular biology. In addition, it has expertise in the development of AAV virus and lentivirus vectors for the development of disease models and the evaluation of new avenues of treatment.
This platform can be used to develop relevant animal models for diseases, particularly those involving the administration of viral vectors according to experimental procedures (anesthesia, recovery etc.) validated in nonhuman primates and rodents (rats, mice). Also to test new treatments based on the injection of viral vectors or cell grafts.
This platform offers a battery of motor and cognitive tests for rodents and nonhuman primates. These tests can be used to validate animal models of human diseases and evaluate the efficacy of new treatments.
The imaging platform provides equipment and expertise in the imaging of the central nervous system by nuclear magnetic resonance (NMR) and positron emission tomography (PET).
The experimental pathology platform is equipped according to highest technical standards for realization of post mortem analysis of non-human primates and rodents in animal facilities with biosecurity levels A1 and A3. It provides macroscopic, histopathologic and molecular analysis of fresh, frozen or fixed tissues.
The Image Processing Platform is responsible for the two- and three-dimensional processing of data generated by histology or imaging in vivo and for the quantitative and statistical analysis of results.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.